Expert Analysis:
Stem Cells & Regenerative Medicine

July 8, 2016

Patient deaths halt clinical trial testing genetically engineered cells to treat cancer

Three patients have died in a clinical trial that is testing the use of genetically engineered immune cells known as CAR-T cells to treat acute lymphoblastic leukemia in adults. Continue reading

May 19, 2016

Mitochondrial replacement: Study identifies challenge for effectiveness of potential therapies

Researchers report that a small amount of mitochondrial DNA carried over in mitochondrial replacement techniques can occasionally increase over time, which could pose a problem for clinical therapies aiming to completely remove faulty mitochondrial DNA. Continue reading

May 4, 2016

Scientists break record for lab-grown human embryos, raising questions over research rules

Two separate research teams publishing in Nature and Nature Cell Biology have reported culturing human embryos up to 13 days, raising questions over international agreement to limit embryo research to 14 days of development. Continue reading

March 4, 2016

Zika virus infects lab-grown brain cells, suggests link to birth defects

New research finds the Zika virus can infect neural cells crucial for brain development in embryos, suggesting a potential biological explanation for the cases of microcephaly seen in Latin America during the Zika outbreak. Continue reading

February 25, 2016

World first: Mouse stem cells used to make sperm-like cells which produce fertile offspring

Researchers have coaxed mouse embryonic stem cells into sperm-like cells which were then used to create fertile offspring. The authors, who describe their technique in Cell Stem Cell, say it could hold “tremendous promise” for treating male infertility in humans. Continue reading

July 15, 2015

Stem cells offer alternative approach to develop therapies for inherited mitochondrial disorders

Genetically corrected pluripotent stem cells derived from patients with inherited mitochondrial disorders offer a new approach to developing therapies for these incurable diseases, according to a study published in Nature Continue reading