Expert Analysis:

July 12, 2016

Red hair gene variants associated with increased mutations in skin cancer

Skin cancer patients who have variations in the MC1R gene, linked to red hair and freckles, have more mutations in their tumors, according to a study in Nature Communications. Continue reading

June 15, 2016

WHO cancer agency: ‘Very hot beverages’ can probably cause cancer in humans

Very hot beverages consumed at more than 65°C can probably cause cancer of the esophagus, according to the International Agency for Research on Cancer (IARC). The classification only evaluates the potential of a substance to cause cancer and does not indicate the level of risk to people’s health, according to the agency. Continue reading

January 12, 2016

Will liquid biopsy technology lead to pan-cancer screening tests?

Research institutions and companies are developing tests that can detect the presence of cancer using small fragments of DNA from tumors which have escaped into the bloodstream; so-called ‘liquid biopsies’. Illumina, the industry-leader in DNA sequencing, recently announced formation of a company to develop a blood test that can detect any kind of cancer at an early stage. Continue reading

December 16, 2015

New analysis finds environmental factors, not random mutations, contribute to majority of cancer risk

Researchers publishing in Nature calculated that 70-90% of the risk of developing cancer can be attributed to extrinsic, environmental factors such as ultraviolet radiation and carcinogens rather than intrinsic factors such as random DNA mutations. Continue reading

November 18, 2015

Genetic mutations linked to cancer inherited by 1 in 12 childhood cancer patients

A study found one in twelve childhood cancer patients had inherited genetic mutations from their parents which predispose them to developing cancer. The authors suggest their findings make a case for genomic screening of all pediatric cancer patients, and the families of patients with inherited mutations. Continue reading

November 9, 2015

Higher meat consumption and genetic factors linked to increased risk of kidney cancer

Consuming high levels of red and white meat was linked to an increased risk of kidney cancer, especially when cooked at high temperatures and among individuals with certain genetic variants, according to research published in the journal CANCER. Continue reading

July 24, 2015

Two classes of generic drugs can improve survival rates in postmenopausal women with early breast cancer

Two classes of generic drugs, aromatase inhibitors and bisphosphonates, can reduce deaths in postmenopausal women with early breast cancer suggest the results of meta-analyses conducted by Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) and published in The Lancet. Continue reading

April 23, 2015

Fewer cancer deaths for women with BRCA1 mutation who had ovaries removed

Removal of ovaries in women after breast cancer diagnosis with a mutation in the BRCA1 gene, a known risk factor for developing breast cancer, was associated with a significant reduction in cancer deaths in a study in JAMA Oncology. Continue reading