Expert Analysis:
Gene Therapies

June 21, 2016

First clinical trial using CRISPR approved by National Institutes of Health advisory panel

A proposal for the first clinical trial involving CRISPR-Cas9 gene editing has been approved by the National Institutes of Health Recombinant DNA Advisory Committee. The Phase I trial, which will require approval from the Food and Drug Administration, is designed … Continue reading

May 20, 2016

Researchers report using CRISPR to remove HIV DNA in live animals for the first time

The removal of HIV virus DNA from the genomes of live animals using CRISPR-Cas9 has been reported in the journal Gene Therapy. Continue reading

April 27, 2016

Company claims success in ‘anti-aging’ gene therapy after trial on CEO

The biotech company Bioviva has claimed that its CEO, Elizabeth Parrish, has successfully had her telomeres lengthened by one of the company’s experimental gene therapies. Continue reading

April 20, 2016

CRISPR made even more precise, used to correct mutations linked to disease risk

Researchers have developed a modified version of CRISPR-Cas9 that can edit single letters of DNA without breaking the double helix, according to a paper in Nature. The authors say their method is more efficient and has fewer off-target effects than previous methods. Continue reading

December 3, 2015

Organizers of global scientific meeting back cautious use of gene-editing in humans

At the close of the international summit on human gene-editing, the organizers released a statement saying it would be “irresponsible to proceed with any clinical use of germline editing” until the risks were better understood, but fell short of endorsing a moratorium on human germline gene-editing. Continue reading